Sunday, March 1, 2015

Endocrine: SIADH and Demeclocycline

I was reading my comprehensive final notes and scribbled in the corner next to "SIADH tx: fluid restrictions Na+ supplements per electrolyte panel and osmolality" was this note: "Declocycline = TX."  No explanation.  And you know me, I hate it when there isn't an explanation, so I Google'd around and found an explanation.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2425217/
http://www.webmd.com/drugs/2/drug-9113/declomycin-oral/details
http://www.medicinenet.com/demeclocycline-oral/article.htm

Demeclocycline (Declocycline) increases the amount of water in the urine (normal specific gravity is 1.010-1.030).



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